I can’t speak for base/mid layers, but I wear merino wool socks at work (danish endurance, not 100% but a blend), in steel toe boots, and they last quite a while. Haven’t had any holes or even wearing thin, and I’m notoriously hard on socks and footwear.

Assetto Corsa (assuming mods are included) and Factorio (again, with mods, but to a lesser degree).