New gene-editing therapy shows early success in fighting advanced GI cancers
med.umn.edu
Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI) cancers. The results, recently published in Lancet Oncology, show encouraging signs of safety and potential effectiveness of the treatment.
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The original was posted on /r/science by /u/mvea on 2025-05-08 10:06:26+00:00.

Original Title: First-in-human clinical trial testing CRISPR/Cas9 gene-editing in 12 highly metastatic, end-stage GI cancer patients saw several of their cancer growth halt, and one patient had a complete response - metastatic tumors disappeared over course of several months and have not returned in over two years.